1352965-57-1Relevant articles and documents
PdII-catalyzed C-H olefination of N-(2-pyridyl)sulfonyl anilines and arylalkylamines
Garcia-Rubia, Alfonso,Urones, Beatriz,Gomez Arrayas, Ramon,Carretero, Juan C.
, p. 10927 - 10931 (2012/01/04)
Flexible friend: The N-(2-pyridyl)sulfonyl group acts as a removable directing group in the PdII-catalyzed aryl C-H ortho alkenylation of N-alkyl aniline, benzylamine, and phenethylamine derivatives with electron-poor alkenes. The products were obtained in high yields (70-90 %) and with complete regiocontrol. The mild reductive N-sulfonyl removal enables the construction of a variety of nitrogen heterocycles. EWG=electron-withdrawing group.