135299-47-7Relevant academic research and scientific papers
Synthesis and reactivity of 2-(1,3-dithian-2-yl)indoles. IV. Influence of the N,N-deithylcarbamoyl indole protecting group
Castells,Troin,Diez,Rubiralta,Grierson,Husson
, p. 7911 - 7924 (2007/10/02)
The effect of the N,N-diethylcarbamoyl indole protecting group on the reactivity of 2-(1,3-dithian-2-yl)indole 7 in front of a series of electrophiles, as well as the potential synthetic usefulness of the resulting 2,2-disubstituted dithianes is reported.
SYNTHETIC APPLICATIONS OF 2-(1,3-DITHIAN-2-YL)INDOLES. III. A NEW ROUTE TO TETRACYCLIC INTERMEDIATES IN THE SYNTHESIS OF ASPIDOSPERMA INDOLE ALKALOIDS
Troin, Yves,Diez, Anna,Bettiol, Jean-Luc,Rubiralta, Mario,Grierson, David S.,Husson, Henri-Philippe
, p. 663 - 668 (2007/10/02)
The synthesis of tetracyclic framework of Aspidosperma alkaloids has been achieved via allylamine-enamine isomerization using (Ph3P)RhCl in hot aqueous acetonitrile of the 1,2,5,6-tetrahydro-3-(indolylethyl)pyridine (13) which in turn was obtained by Raney nickel desulfurization of the corresponding 2-(1,3-dithian-2-yl)indole (5a).
