1353000-40-4Relevant academic research and scientific papers
CuCl/DABCO/4-HO-TEMPO-catalyzed aerobic oxidative synthesis of 2-substituted quinazolines and 4 H -3,1-benzoxazines
Han, Bing,Yang, Xiu-Long,Wang, Chao,Bai, Yong-Wei,Pan, Tai-Chao,Chen, Xin,Yu, Wei
, p. 1136 - 1142 (2012/02/16)
The Cu/N-ligand/TEMPO catalytic system was first applied to the aerobic oxidative synthesis of heterocycles. As demonstrated, 2-substituted quinazolines and 4H-3,1-benzoxazines were synthesized efficiently from the one-pot reaction of aldehydes with 2-aminobenzylamines and 2-aminobenzyl alcohols, respectively, by employing CuCl/DABCO/4-HO-TEMPO as the catalysts and oxygen as the terminal oxidant.
