1353000-88-0Relevant articles and documents
Synthesis and preliminary screening of novel a- and D-ring modified steroids as aromatase inhibitors
Yadav, Mange Ram,Sabale, Prafulla M.,Giridhar, Rajani,Baria, Dharmendra,Zimmer, Christina,Hartmann, Rolf W.
, p. 943 - 950 (2011)
Estrogens are responsible for the growth of hormone-dependant breast cancer. Regulation of estrogen biosynthesis is considered as a potential therapeutic strategy for the control of breast cancer. The enzyme aromatase catalyzes conversion of androgens int