1353042-48-4Relevant articles and documents
Expanding the scope of the direct regiospecific asymmetric aldol reaction to enones and dienones catalyzed by a BINOL-derived bronsted acid
Das, Joydeb,Le Cavelier, Fabien,Rouden, Jacques,Blanchet, Jerome
experimental part, p. 6628 - 6631 (2012/01/04)
Chiral phosphoric acid (R)-1a has been shown to be an efficient Bronsted acid catalyst for the useful asymmetric synthesis of various acyclic and endo-and exocyclic β-hydroxyenones through a regiospecific aldol reaction between α,β-unsaturated ketones and ethyl glyoxalate. Moreover, two unprecedented examples involving sensitive dienones are reported.