1353054-35-9Relevant academic research and scientific papers
New strigolactone mimics: Structure-activity relationship and mode of action as germinating stimulants for parasitic weeds
Zwanenburg, Binne,Nayak, Sandip K.,Charnikhova, Tatsiana V.,Bouwmeester, Harro J.
, p. 5182 - 5186 (2013)
Strigolactones (SLs) are new plant hormones with varies important bio-functions. This Letter deals with germination of seeds of parasitic weeds. Natural SLs have a too complex structure for synthesis. Therefore, there is an active search for SL analogues and mimics with a simpler structure with retention of activity. SL analogues all contain the D-ring connected with an enone moiety through an enol ether unit. A new mechanism for the hydrolysis SL analogues involving bidentate bound water and an α,β-hydrolase with a Ser-His-Asp catalytic triad has been proposed. Newly discovered SL mimics only have the D-ring with an appropriate leaving group at C-5. A mode of action for SL mimics was proposed for which now supporting evidence is provided. As predicted an extra methyl group at C-4 of the D-ring blocks the germination of seeds of parasitic weeds.
Strigolactone analogues and mimics derived from phthalimide, saccharine, p-tolylmalondialdehyde, benzoic and salicylic acid as scaffolds
Zwanenburg, Binne,Mwakaboko, Alinanuswe S.
experimental part, p. 7394 - 7400 (2012/01/14)
A series of new strigolactone (SL) analogues is derived from simple and cheap starting materials. These SL analogues are designed using a working model. The first analogue is a modified Nijmegen-1, the second contains saccharin as substituent (bio-isoster
