1353101-72-0

Basic information

• Product Name: N-benzyl-3-chloropyridin-4-amine
• Synonyms: N-benzyl-3-chloropyridin-4-amine
• CAS NO: 1353101-72-0
• Molecular Weight: 218.686
• Mol File: 1353101-72-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-3-chloropyridin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-3-chloropyridin-4-amine(1353101-72-0)
• EPA Substance Registry System: N-benzyl-3-chloropyridin-4-amine(1353101-72-0)

Safety Data

• Hazardous Substances Data: 1353101-72-0(Hazardous Substances Data)

Upstream product

• 19798-77-7 4-amino-3-chloropyridine 
• 100-52-7 benzaldehyde 

Downstream Products

• 1436853-12-1 N-benzyl-2-chloro-2-(3-chloropyridin-4-yl)acetamide 

Relevant articles and documents

Rearrangement of 4-amino-3-halo-pyridines by nucleophilic aromatic substitution

The reaction of 3-halo-4-aminopyridines with acyl chlorides and triethylamine is described. The pyridin-4-yl α-substituted acetamide products were obtained in moderate to high yields. The presented rearrangement reaction, in which the presumed N-acylated intermediate reacts intramolecularly via nucleophilic aromatic substitution, results in a formal two-carbon insertion.