1353170-37-2Relevant academic research and scientific papers
Efficient synthesis of DNA conjugates by strain-promoted azide-cyclooctyne cycloaddition in the solid phase
Singh, Ishwar,Freeman, Colin,Heaney, Frances
, p. 6739 - 6746 (2011)
Conjugation of ligands to DNA oligonucleotides has been achieved in the solid phase by strain-promoted azide-alkyne cycloaddition (SPAAC). The oligonucleotide, modified with a simple nonfluroinated, monocyclic octyne, efficiently forms conjugates with a r
