135319-73-2

Basic information

• Product Name: (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole
• Synonyms: (2rs,3sr)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1h-1,2,4-triazole;EPOXICONAZOLE;EPOCICONAZOLE;Epoxiconazole-2
• CAS NO: 135319-73-2
• Molecular Formula: C₁₇H₁₃ClFN₃O
• Molecular Weight: 329.76
• EINECS: 603-915-9
• Mol File: 135319-73-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 463.1 °C at 760 mmHg
• Flash Point: 233.9 °C
• Appearance: /
• Density: 1.39 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.659
• PKA: 2.75±0.10(Predicted)
• CAS DataBase Reference: (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole(135319-73-2)
• EPA Substance Registry System: (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole(135319-73-2)

Safety Data

• Hazard Codes: Xn:Harmful;;
• Statements: R40:; R51/53:; R62:; R63:
• Safety Statements: S36/37:; S46:; S61:
• Hazardous Substances Data: 135319-73-2(Hazardous Substances Data)

Usage

Description

(2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole, commonly known as Epoxiconazole, is a member of the triazole class of fungicides. It is characterized by its unique chemical structure that includes a 1,2,4-triazole ring fused with a 2,3-epoxypropyl group and substituted with a 2-chlorophenyl and a 4-fluorophenyl group. (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole is designed to inhibit fungal growth by interfering with the synthesis of ergosterol, an essential component of fungal cell membranes.

Uses

Used in Agricultural Industry:
Epoxiconazole is used as a fungicide for the protection of various crops. It is effective against a broad spectrum of fungal diseases, such as powdery mildew, rust, and leaf spot, which can cause significant yield losses and affect the quality of the produce. By targeting the ergosterol synthesis in fungi, Epoxiconazole helps to prevent the growth and spread of these diseases, ensuring healthier crops and improved agricultural productivity.
Used in Plant Protection:
In addition to its application in agriculture, Epoxiconazole is also used in plant protection to safeguard ornamental plants and turf grasses from fungal infections. Its systemic action allows it to be absorbed by the plant and distributed throughout the tissues, providing long-lasting protection against a range of fungal pathogens. This helps to maintain the aesthetic appeal and health of landscapes, gardens, and sports fields.

InChI:InChI=1/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2/t16-,17-/m0/s1

Upstream product

• 288-88-0 1,2,4-Triazole 
• 150344-44-8 2-chlorobenzyl 4-fluorophenyl ketone 
• 350-40-3 2-(4-fluorophenyl)-1-propene 
• 615-41-8 2-iodochlorobenzene 
• 95-50-1 1,2-dichloro-benzene 

Relevant articles and documents

Method for reducing 1,3,4-triazole substituent in 1,2,4-triazole alkylation reaction process

The invention relates to a method for reducing a 1,3,4-triazole substituent in 1,2,4-triazole alkylation reaction process. The method comprises the steps that 1, 2, 4-triazole and an alkylation reagent are subjected to an alkylation reaction in the presence of an alkali and a catalyst, after the reaction is finished, 1, 2, 4-triazole substituent is obtained through aftertreatment, and the catalystis one or a combination of more of polyether, cyclic crown ether, quaternary ammonium salt, quaternary phosphorus salt, quaternary ammonium base and tertiary amine. The method is simple to operate; the method is wide in application range, the content of the 1, 3, 4-triazole substituent in the alkylation reaction process can be reduced, the yield of the 1, 2, 4-triazole substituent is increased, the reaction time is shortened, the reaction temperature is reduced, solvent use is reduced or avoided, the resource utilization rate is increased, three wastes are reduced, the production cost is reduced, and the method meets the requirements of a green and environment-friendly process.

Epoxiconazole intermediate, preparation method thereof, and preparation method of epoxiconazole

The invention relates to an epoxiconazole intermediate, a preparation method thereof, and a preparation method of epoxiconazole. The epoxiconazole intermediate is a compound with a structural formulaIII shown in the description, and X in the formula III is Br or Cr. The preparation methods have the advantages of cheap and easily available raw materials, simple steps, high safety, few pollution ofthree wastes, mild reaction conditions, green, clean and environmentally-friendly reagents and reaction processes, suitableness for industrial production, and realization of high yield and high content of the final products.

FUNGICIDAL MIXTURES

The present invention relates to fungicidal mixtures comprising, as active components, 1) azolylmethyloxiranes of the general formula I wherein the variables have the meanings described in the application, 2) a fungicidal compound II, and 3) optionally a further fungicidal compound II, where the compounds II of components 2 and 3 independently of one another are selected from the group consisting of the compounds described in the application, with the proviso that components 2 and 3 are not identical, and to the use of the fungicidal mixtures for controlling phytopathogenic fungi and to the compositions comprising them.