135328-53-9 Usage
Derivative of indole
Heterocyclic aromatic organic compound
1H-Indole, 7-(triphenylmethoxy)is derived from indole, which is a heterocyclic (containing a ring of atoms with at least one non-carbon atom) aromatic (having a stable, delocalized electron system) organic compound.
Triphenylmethoxy group
Presence on the 7th carbon of the indole ring
A triphenylmethoxy group (a methoxy group attached to three phenyl groups) is attached to the 7th carbon of the indole ring, giving 1H-Indole, 7-(triphenylmethoxy)- its unique properties.
Potential applications
Medicinal chemistry and pharmaceuticals
1H-Indole, 7-(triphenylmethoxy)has potential applications in the field of medicinal chemistry and pharmaceuticals due to its diverse biological activities.
Biological activities
Anti-cancer, anti-inflammatory, and antimicrobial properties
Indole derivatives, including 1H-Indole, 7-(triphenylmethoxy)-, have been studied for their various biological activities, such as anti-cancer (inhibiting cancer cell growth), anti-inflammatory (reducing inflammation), and antimicrobial (fighting infections caused by microorganisms) properties.
Specific properties and uses
Vary depending on synthesis and formulation
The specific properties and uses of 1H-Indole, 7-(triphenylmethoxy)may differ based on the methods used in its synthesis (chemical reactions to create the compound) and formulation (preparation of the compound for specific applications).
Check Digit Verification of cas no
The CAS Registry Mumber 135328-53-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,3,2 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 135328-53:
(8*1)+(7*3)+(6*5)+(5*3)+(4*2)+(3*8)+(2*5)+(1*3)=119
119 % 10 = 9
So 135328-53-9 is a valid CAS Registry Number.
135328-53-9Relevant academic research and scientific papers
Certain indole derivatives useful as leukotriene antagonists
-
, (2008/06/13)
A compound of the formula STR1 in which R1 is hydrogen, halo, C1-4 alkyl, C1-4 alkoxy, nitrile, optionally protected carboxy, optionally protected tetrazolyl, trihalomethyl, hydroxy-C1-4 alkyl, aldehydo, --CH2 Z, --CH=CH--Z or --CH2 CH2 Z where Z is optionally protected carboxy or optionally protected tetrazolyl; R2 is halo, nitrile, an optionally protected acid group or --CONR7 R8 where R7 and R8 are each hydrogen or C1-4 alkyl; R3 and R4 are each hydrogen, C1-4 alkyl, optionally substituted phenyl, or C1-4 alkyl substituted by --CONR7 R8 or an optionally protected acid group; R5 is STR2 where W is --CH=CH--, --CH=N--, --N=CH--, --O-- or --S--, R9 is hydrogen, halo, C1-4 alkyl, C1-4 alkoxy or trihalomethyl, and R10 is hydrogen, C1-4 alkyl, C2-6 alkenyl, C3-6 cycloalkyl or C1-4 alkyl-C3-6 cycloalkyl; R6 is hydrogen or C1-4 alkyl; X is --O--(CH2)n CR11 R12, --CR11 R12 --, --CR11 R12.(CH2)n.CR13 R14 -- or --CR11 =CR12 -- where R11, R12, R13 and R14 are each hydrogen or C1-4 alkyl, and n is 0, 1 or 2; and Y is --O--CR15 R16 --, --CR15 =CR16 -- or --CR15 R16.CR17 R18 -- where R15, R16, R17 and R18 are each hydrogen or C 1-4 alkyl; or a salt thereof. The compounds in unprotected form are active as leukotriene antagonists.
The synthesis of 7-alkoxyindoles
Dobson,Todd,Gilmore
, p. 611 - 617 (2007/10/02)
A number of protected 7-hydroxyindoles was prepared by reaction of the protected 2-nitrophenols with vinylmagnesium bromide. Benzhydryl was shown to be the protecting group of choice, giving good yields of the indole and being readily removed for subsequent transformations of the 7-hydroxy function.
