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(E)-1-chloro-1-(4E)-4-[chloro(nitroso)methylidene]cyclohexa-2,5-dien-1-ylidene-N-hydroxymethanamine, commonly known as nitrosochloromethane, is a chemical compound characterized by its molecular formula C7H8Cl2NO. This colorless, highly reactive liquid with a pungent odor is classified as a chloroalkene and a nitro compound. Due to its toxicity and reactivity, nitrosochloromethane is considered a potentially hazardous chemical, necessitating careful handling and strict regulation in its use to protect human health and the environment.

13533-12-5

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13533-12-5 Usage

Uses

Used in Organic Synthesis:
Nitrosochloromethane is utilized as a key intermediate in the production of various chemical compounds. Its reactivity allows for its incorporation into a wide range of organic synthesis processes, making it a valuable compound in the chemical industry.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, nitrosochloromethane may be employed as a building block for the synthesis of pharmaceutical compounds. Its unique structure and reactivity enable the creation of novel drug candidates with potential therapeutic applications.
Used in Chemical Research:
Due to its reactivity and structural characteristics, nitrosochloromethane is also used in chemical research to study reaction mechanisms, explore new synthetic pathways, and develop innovative chemical processes.
Used in Environmental Monitoring:
Nitrosochloromethane's potential hazards highlight the need for its monitoring in industrial settings. It is used in environmental monitoring applications to ensure that its levels are kept within safe limits, thereby protecting workers and the environment from its toxic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 13533-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,3 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13533-12:
(7*1)+(6*3)+(5*5)+(4*3)+(3*3)+(2*1)+(1*2)=75
75 % 10 = 5
So 13533-12-5 is a valid CAS Registry Number.

13533-12-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Terephthalohydroximoyl chloride

1.2 Other means of identification

Product number -
Other names benzene-1,4-dicarboxaldehyde dioxime

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13533-12-5 SDS

13533-12-5Relevant academic research and scientific papers

One-pot synthesis of precise polyisoxazoles by click polymerization: Copper (I)-catalyzed 1,3-dipolar cycloaddition of nitrile oxides with alkynes

Li, Yan,Cheng, Bin

, p. 1645 - 1650 (2013)

This article reports a new one-pot method for polymer preparation, which involves double click chemistry. In one pot, two click reactions take place sequentially by adding the reactants step by step. The first click reaction is to produce the monomer for

Preparation of novel Di-isoxazolines using bis(nitrile oxide) 1,3-dipolar cycloaddition methodology

Bigdeli, Mohammad Ali,Halimehjani, Azim Ziyaei,Mohammadipour, Mohammad,Sagharichi, Parishad

, p. 926 - 928 (2012/10/29)

A general method for the synthesis of novel di-isoxazolines through a 1,3-dipolar cycloaddition reaction of in situ prepared bis (nitrile oxides) of terephthaldehyde and various olefins is described. The reactions are regiospecific and give high yields of

Synthesis of 1,3- and 1,4-bis(3-nitrofurazan-4-yl)benzenes and isomeric 1,3- and 1,4-bis[3(4)-nitrofuroxan-4(3)-yl]benzenes

Ovchinnikov, Igor V.,Finogenov, Alexey O.,Epishina, Margarita A.,Strelenko, Yuri A.,Makhova, Nina N.

scheme or table, p. 217 - 219 (2009/12/05)

The 1,3- and 1,4-bis(3-nitrofurazan-4-yl)benzenes have been synthesized by dehydration of 1,3- and 1,4-bis(2-aminoglyoximo- 1-yl)benzenes followed by oxidation of amino groups. The 1,3- and 1,4-bis(3-nitrofuroxan-4-yl)benzenes have been prepared by nitroz

Multiple Cycloadditive macrocyclization: An Efficient Method for Crown Ether-Type Cyclophanes, Bis-Calix[4]arenes and Silamacrocycles

Kim, Byeang Hyean,Jeong, Eun Jeong,Hwang, Gil Tae,Venkatesan, Natarajan

, p. 2191 - 2202 (2007/10/03)

Macrocycles constitute a broad spectrum of compounds, which play a significant role in host-guest supramolecular chemistry. We have rationally designed an efficient novel synthetic method to synthesize different types of artificial receptive macrocycles containing isoxazoline or isoxazole ring systems. This method involves multiple (double, triple or quadrupole) cycloadditions between bifunctional dipoles and bifunctional dipolarophiles. We have presented our synthetic results to show the ease with which this one-pot synthetic method can be extended to synthesize different types of macrocycles such as cyclophanes, bis-calix[4]arenes and silamacrocycles. Hence, with appropriate combination of bifunctional dipoles and bifunctional dipolarophiles, the ring size of macrocycles could be controlled. This multiple cycloadditive macrocyclization will be a useful arsenal for the synthesis of various macrocycles.

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