1353557-76-2Relevant academic research and scientific papers
Stereospecific cross-coupling between alkenylboronates and alkyl halides catalyzed by iron-bisphosphine complexes
Hashimoto, Toru,Hatakeyama, Takuji,Nakamura, Masaharu
, p. 1168 - 1173 (2012)
A stereospecific and high-yielding cross-coupling reaction between alkenylboron reagents and alkyl halides is described. The reaction has been achieved by using well-defined iron-bisphosphine complexes such as 1b FeCl 2(3,5-t-Bu2-SciOPP), which was recently developed by the authors' group. Various nonactivated alkyl bromides and chlorides possessing a base/nucleophile-sensitive functional group can participate in the cross-coupling, demonstrating its utility for stereoselective synthesis of functional molecules bearing a carbon-carbon double bond.
