1353577-09-9Relevant articles and documents
Total synthesis of (R)-(-)-actisonitrile via O-alkylation of optically active 4-hydroxymethyloxazolidin-2-one derivative
Sugiyama, Shigeo,Ishida, Akihiro,Tsuchida, Moeko,Ishii, Keitaro
experimental part, p. 1918 - 1923 (2012/02/05)
The enantioselective synthesis of (R)-(-)-actisonitrile 1 has been achieved via O-alkylation of (4R,αS)-4-hydroxymethyl-3-(α-methylbenzyl) oxazolidin-2-one (αS)-4 with 1-iodohexadecane in the presence of CsOH in DMF. Under these reaction conditions, the O