1353585-33-7Relevant academic research and scientific papers
PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN
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Page/Page column 30, (2012/01/13)
Disclosed are compounds, compositions and methods for treating pain, including inflammatory, visceral, and acute pain. Such compounds are represented by Formula (I) as follows: wherein A1, L1, D, and Q are defined herein.
Triazinediones as prokineticin 1 receptor antagonists. Part 1: SAR, synthesis and biological evaluation
Ralbovsky, Janet L.,Lisko, Joseph G.,Palmer, Jeffrey M.,Mabus, John,Chevalier, Kristen M.,Schulz, Mark J.,Dyatkin, Alexey B.,Miskowski, Tamara A.,Coats, Steven J.,Hornby, Pamela,He, Wei
scheme or table, p. 2661 - 2663 (2009/12/31)
A series of guanidine triazinediones were identified as potent PK1 receptor antagonists. A compound in this series inhibited the PK1 invoked prosecretory response in rat ileum tissue.
PROKINETICIN 2 RECEPTOR ANTAGONISTS
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Page/Page column 87, (2010/11/28)
The present invention relates to certain novel compounds of Formula (I): and methods for the treatment of prokineticin 2 or prokinetin 2 receptor mediated disorders.
