1353967-23-3

Basic information

• Product Name: 2-(5-chloro-2-fluoro-phenyl)-4-[1-(2-methoxy-ethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-[1,8]naphthyridine
• Synonyms: 2-(5-chloro-2-fluoro-phenyl)-4-[1-(2-methoxy-ethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-[1,8]naphthyridine
• CAS NO: 1353967-23-3
• Molecular Weight: 432.885
• Mol File: 1353967-23-3.mol

Chemical Properties

• CAS DataBase Reference: 2-(5-chloro-2-fluoro-phenyl)-4-[1-(2-methoxy-ethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-[1,8]naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-chloro-2-fluoro-phenyl)-4-[1-(2-methoxy-ethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-[1,8]naphthyridine(1353967-23-3)
• EPA Substance Registry System: 2-(5-chloro-2-fluoro-phenyl)-4-[1-(2-methoxy-ethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-[1,8]naphthyridine(1353967-23-3)

Safety Data

• Hazardous Substances Data: 1353967-23-3(Hazardous Substances Data)

Upstream product

• 1323919-45-4 2-(5-chloro-2-fluoro-phenyl)-[1,8]naphthyridine-4-boronic acid 
• 1353969-86-4 3-iodo-1-(2-methoxy-ethyl)-1H-pyrrolo[2,3-c]pyridine 
• 1323919-28-3 4-chloro-2-(5-chloro-2-fluoro-phenyl)-[1,8]naphthyridine 
• 956003-24-0 3-iodo-1H-pyrrolo[2,3-c]pyridine 
• 59514-89-5 2,4-dichloro-[1,8]naphthyridine 
• 13362-26-0 2-aminopyridine-3-carboxylic acid ethyl ester 
• 59514-86-2 [1,8]naphthyridine-2,4-diol 
• 5345-47-1 2-aminopyridin-3-carboxylic acid 

Relevant articles and documents

2,4- DIARYL-SUBSTITUTED [1,8] NAPHTHYRIDINES AS KINASE INHIBITORS FOR USE AGAINST CANCER

The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases playsa role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors