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Mechanistic studies on a new catalyst system (CuI-NaHSO4· SiO2) leading to the one-pot synthesis of imidazo[1,2- a ]pyridines from reactions of 2-aminopyridines, aldehydes, and terminal alkynes
Mishra, Sarita,Ghosh, Rina
scheme or table, p. 3463 - 3470 (2011/12/04)
One-pot reactions of aldehydes, 2-aminopyridines, and terminal alkynes, in the presence of the copper(I) iodide-NaHSO4·SiO2 combination catalyst in refluxing toluene, generate the corresponding imidazo[1,2-a]pyridines in high to excellent yields; the mechanism has been studied. Georg Thieme Verlag Stuttgart.
