1353998-68-1

Basic information

• Product Name: (3R,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol
• Synonyms: (3R,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol
• CAS NO: 1353998-68-1
• Molecular Weight: 368.591
• Mol File: 1353998-68-1.mol

Chemical Properties

• CAS DataBase Reference: (3R,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol(1353998-68-1)
• EPA Substance Registry System: (3R,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol(1353998-68-1)

Safety Data

• Hazardous Substances Data: 1353998-68-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(3R,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol is used as a building block for the preparation of various biologically active molecules and pharmaceuticals. Its unique structure and reactivity contribute to the development of complex organic compounds in the field of organic synthesis.

Upstream product

• 117438-29-6 (R)-6-methyl-5-hepten-2-yl acetate 
• 58917-27-4 (R)-sulcatol 
• 4630-06-2 6-methylhept-5-en-2-ol 
• 1073630-49-5 (R)-6-tert-butyldiphenylsilyloxy-2-methyl-2-heptene 
• 162971-56-4 (R)-4-<(tert-butyldiphenylsilyl)oxy>pentan-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 126680-65-7 5-((tert-butyldimethylsilyl)oxy)pentan-2-ol 
• 626-95-9 1,4-Pentanediol 
• 1353998-64-7 C₁₃H₂₈O₃Si 
• 1353998-67-0 C₂₃H₃₀O₂Si 
• 1353998-66-9 (3RS,6R)-6-tert-butyldiphenylsilyloxyhept-1-en-3-ol 
• 1353998-65-8 C₂₇H₄₄O₂Si₂ 
• 1307273-43-3 (R)-4-tert-butyldiphenylsilyloxypentanal 
• 1392409-20-9 (R)-5-[[dimethyl(1,1-dimethylethyl)-silyl]oxy]-2-pentanol 

Downstream Products

• 1353998-69-2 C₂₆H₃₈O₃Si 

Relevant articles and documents

A chemoenzymatic synthesis of hept-6-ene-2,5-diol stereomers: Application to asymmetric synthesis of decarestrictine L, pyrenophorol, and stagonolide e

The stereomers of hept-6-ene-2,5-diol derivatives were conceived as useful chiral intermediates and were synthesized starting from sulcatol using two lipase-catalyzed acylation reactions as the key steps. The versatility of the intermediates was demonstrated by converting them to the titled tetrahydropyran, macrolide, and macrodiolide compounds using standard synthetic protocols.

Chemoenzymatic total synthesis of stagonolide-E

Asymmetric total synthesis of small ring macrolide stagonolide-E has been described in this communication. The main highlight of our synthetic strategy is the application of ME-DKR (metal enzyme combo dynamic kinetic resolution) reaction, asymmetric reduc