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1354035-55-4

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1354035-55-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1354035-55-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,4,0,3 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1354035-55:
(9*1)+(8*3)+(7*5)+(6*4)+(5*0)+(4*3)+(3*5)+(2*5)+(1*5)=134
134 % 10 = 4
So 1354035-55-4 is a valid CAS Registry Number.

1354035-55-4Relevant academic research and scientific papers

Discovery of naphthyl-fused 5-membered lactams as a new class of M 1 positive allosteric modulators

Yang, Zhi-Qiang,Shu, Youheng,Ma, Lei,Wittmann, Marion,Ray, William J.,Seager, Matthew A.,Koeplinger, Kenneth A.,Thompson, Charles D.,Hartman, George D.,Bilodeau, Mark T.,Kuduk, Scott D.

supporting information, p. 604 - 608 (2014/06/09)

Selective activation of the M1 muscarinic receptor via positive allosteric modulation represents an original approach to treat the cognitive decline in patients with Alzheimer's disease. A series of naphthyl-fused 5-membered lactams were identified as a new class of M1 positive allosteric modulators and were found to possess good potency and in vivo efficacy.

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