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135415-89-3

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135415-89-3 Usage

General Description

(R)-2-Hydroxy-2-methyl-hexanenitrile is a chemical compound with the molecular formula C7H13NO. It is a colorless liquid with a fruity odor and is commonly used as a flavoring agent in the food and beverage industry. (R)-2-HYDROXY-2-METHYL-HEXANENITRILE is also used in the production of pharmaceuticals and as a fragrance in perfumes and personal care products. (R)-2-hydroxy-2-methyl-hexanenitrile is classified as a nitrile, which are known for their wide range of applications in organic synthesis and chemical production. It is important to handle this compound with caution due to its potential hazardous properties and to follow proper safety protocols when working with it.

Check Digit Verification of cas no

The CAS Registry Mumber 135415-89-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,4,1 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 135415-89:
(8*1)+(7*3)+(6*5)+(5*4)+(4*1)+(3*5)+(2*8)+(1*9)=123
123 % 10 = 3
So 135415-89-3 is a valid CAS Registry Number.

135415-89-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-2-hydroxy-2-methylhexanenitrile

1.2 Other means of identification

Product number -
Other names (R)-2-Hydroxy-2-Methyl- Hexanenitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:135415-89-3 SDS

135415-89-3Downstream Products

135415-89-3Relevant articles and documents

Synthesis of aliphatic and α-halogenated ketone cyanohydrins with the hydroxynitrile lyase from Manihot esculenta

Diebler, Johannes,Von Langermann, Jan,Mell, Annett,Hein, Martin,Langer, Peter,Kragl, Udo

, p. 987 - 991 (2014/05/06)

The potential of the hydroxynitrile lyase from Manihot esculenta towards ketone substrates was investigated. It was observed that the length of the aliphatic chain is a key parameter for the conversion of aliphatic, non-branched ketones. Smaller substrates are readily converted with high enantioselectivites, but the elongation of the chain length causes a significant loss in enzyme activity. For a number of halogenated, herein especially fluorinated, acetophenone derivatives the corresponding cyanohydrins have been synthesized with good to moderate enantioselectivities. Overcoming limitations: Ketone cyanohydrins are extremely useful intermediates for the synthesis of unusual tertiary alcohols. In this contribution, the limits of the hydroxynitrile lyase from Manihot esculenta towards such substrates are investigated and evaluated. High enantioselectivities are obtained in a simple two-phase system, even with very challenging fluorinated acetophenone derivatives.

Enzymatic Synthesis of (R)-Cyanohydrins by Three (R)-Oxynitrilase Sources in Micro-aqueous Organic Medium

Lin, Guoqiang,Han, Shiqing,Li, Zuyi

, p. 3531 - 3540 (2007/10/03)

The enantioselective synthesis of optically active (R)-cyanohydrins generated from several aromatic, heteroaromatic and aliphatic aldehydes and methyl ketones was carried out using almond, peach or loquat meal as (R)-oxynitrilase sources in diisopropylether under micro-aqueous conditions The micro-aqueous reaction system, which is superior to the conventionally used water-organic biphase reaction system, performed well over the temperature range of 4 deg C to 30 deg C.

Synthesis of (R)-cyanohydrins by crude (R)-oxynitrilase-catalyzed reactions in micro-aqueous medium

Han, Shiqing,Lin, Guoqiang,Li, Zuyi

, p. 1835 - 1838 (2007/10/03)

In diisopropyl ether or ethyl acetate under micro-aqueous conditions, the enantioselective synthesis of (R)-cyanohydrins from aldehydes and methyl ketones was studied using crude (R)-oxynitrilase prepared from almonds. This reaction system performed well

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