1354197-75-3Relevant academic research and scientific papers
Catalytic asymmetric construction of tetrasubstituted carbon stereocenters by conjugate addition of dialkyl phosphine oxides to β,β-disubstituted α,β-unsaturated carbonyl compounds
Zhao, Depeng,Mao, Lijuan,Wang, Linqing,Yang, Dongxu,Wang, Rui
, p. 889 - 891 (2012)
The catalytic asymmetric phospha-Michael reaction of dialkyl phosphine oxides with β,β-disubstituted α,β-unsaturated carbonyl compounds was achieved. The products bearing tetrasubstituted carbon stereocenters were obtained in high yields with excellent enantioselectivities (up to >99% ee).
