1354198-66-5

Basic information

• Product Name: 2-((3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)methyl)-6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
• Synonyms: 2-((3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)methyl)-6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
• CAS NO: 1354198-66-5
• Molecular Weight: 429.401
• Mol File: 1354198-66-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)methyl)-6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)methyl)-6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one(1354198-66-5)
• EPA Substance Registry System: 2-((3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)methyl)-6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one(1354198-66-5)

Safety Data

• Hazardous Substances Data: 1354198-66-5(Hazardous Substances Data)

Upstream product

• 425702-91-6 6-bromo-[1,2,4]triazole[4,3-a]pyridine-3(2H)-one 
• 1171921-06-4 (3-cyclopropyl-1-methyl-1H-pyrazol-5-yl)methanol 
• 1354200-71-7 6-(4-(trifluoromethoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 
• 77992-44-0 5-bromo-2-hydrazinylpyridine 

Relevant articles and documents

Fused Heterocyclic Compounds as Ion Channel Modulators

The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein R1, R2, R3, R4, and R5 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.