1354222-16-4

Basic information

• Product Name: 2-methoxyquinolin-7-amine
• CAS NO: 1354222-16-4
• Molecular Weight: 174.202
• Mol File: 1354222-16-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 335.3±22.0 °C(Predicted)
• Density: 1.217±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-methoxyquinolin-7-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxyquinolin-7-amine(1354222-16-4)
• EPA Substance Registry System: 2-methoxyquinolin-7-amine(1354222-16-4)

Safety Data

• Hazardous Substances Data: 1354222-16-4(Hazardous Substances Data)

Upstream product

• 1354222-15-3 2-methoxy-7-nitroquinoline 
• 49609-03-2 2-chloro-7-nitroquinoline 

Relevant articles and documents

NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF

An object of the present invention is to provide to a compound and a pharmaceutical composition, which have excellent Syk-inhibitory activity. Th e present invention provides a nicotinamide derivative represented by the follo wing formula (I) (wherein R 1 represents a halogen atom; R 2 represents a C 1-12 alkyl group, a C 2-12 alkenyl group, a C 2-12 alkynyl group, a C 3-8 cycloalkyl g roup, an aryl group, an ar-C 1-6 alkyl group or a heterocyclic group, each opti onally having at least one substituent; R 3 represents an aryl group or a hetero cyclic group each optionally having at least one substituent; and R 4 and R 5 e ach independently represent a hydrogen atom; and R 2 and R 4 may form a cyc lic amino group optionally having at least one substituent together with the ni trogen atom to which they bind) or a salt thereof, and a pharmaceutical comp osition for use in the treatment of a Syk-related disease which comprises the nicotinamide derivative or a salt thereof.