1354348-90-5Relevant articles and documents
2,3-Diaroyl benzofurans from arynes: Sequential synthesis of 2-aroyl benzofurans followed by benzoylation
Neog, Kashmiri,Das, Babulal,Gogoi, Pranjal
, p. 3138 - 3150 (2018/05/17)
A cascade synthetic strategy for the direct synthesis of 2-aroyl benzofurans from aryne precursors has been developed. This reaction proceeds via C-O and C-C bond cleavage as well as C-O and C-C bond formation in a single reaction vessel. The methodology provides good yields of 2-aroyl benzofurans and tolerates a variety of functional groups. The synthesized 2-aroyl benzofurans were further benzoylated at 3-positions and one of the synthesized 2,3-diaroyl benzofuran structures was confirmed unambiguously by X-ray crystallography.
Palladium-catalyzed direct arylation of polysubstituted benzofurans
Carrer, Amandine,Brinet, Dimitri,Florent, Jean-Claude,Rousselle, Patricia,Bertounesque, Emmanuel
experimental part, p. 1316 - 1327 (2012/03/27)
An efficient access to 2-substituted 3-arylbenzofurans through a palladium-catalyzed C3 direct arylation of 2-substituted benzofurans with aryl bromides is described. The scope and limitation of this reaction was studied. The method tolerates a variety of functional groups on the aryl halide and has been successfully extended to polysubstituted benzofurans to obtain the corresponding 3-arylbenzofurans with good to excellent yields.
