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135437-78-4

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135437-78-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 135437-78-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,4,3 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 135437-78:
(8*1)+(7*3)+(6*5)+(5*4)+(4*3)+(3*7)+(2*7)+(1*8)=134
134 % 10 = 4
So 135437-78-4 is a valid CAS Registry Number.

135437-78-4Downstream Products

135437-78-4Relevant articles and documents

A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability

Rawson, Thomas E.,Rüth, Matthias,Blackwood, Elizabeth,Burdick, Dan,Corson, Laura,Dotson, Jenna,Drummond, Jason,Fields, Carter,Georges, Guy J.,Goller, Bernhard,Halladay, Jason,Hunsaker, Thomas,Kleinheinz, Tracy,Krell, Hans-Willi,Li, Jun,Liang, Jun,Limberg, Anja,McNutt, Angela,Moffat, John,Phillips, Gail,Ran, Yingqing,Safina, Brian,Ultsch, Mark,Walker, Leslie,Wiesmann, Christian,Zhang, Birong,Zhou, Aihe,Zhu, Bing-Yan,Rüger, Petra,Cochran, Andrea G.

experimental part, p. 4465 - 4475 (2009/07/11)

Aurora kinase inhibitors have attracted a great deal of interest as a new class of antimitotic agents. We report a novel class of Aurora inhibitors based on a pentacyclic scaffold. A prototype pentacyclic inhibitor 32 (AKI-001) derived from two early lead

PYRIMIDINE KINASE INHIBITORS

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Page/Page column 32-33, (2008/06/13)

The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula (I) wherein ring A, X, Y, Z, R1, R2, R3, R4, m and n are as defined herein.

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