1354376-83-2Relevant academic research and scientific papers
Petasis three-component coupling reactions of hydrazides for the synthesis of oxadiazolones and oxazolidinones
Le Quement, Sebastian T.,Flagstad, Thomas,Mikkelsen, Remi J. T.,Hansen, Mette R.,Givskov, Michael C.,Nielsen, Thomas E.
, p. 640 - 643 (2012/03/11)
An application of readily available hydrazides in the Petasis 3-component coupling reaction is presented. An investigation of the substrate scope was performed to establish a general, synthetically useful protocol for the formation of hydrazido alcohols, which were selectively converted to oxazolidinone and oxadiazolone ring systems through triphosgene-mediated cyclization reactions.
