1354495-43-4

Basic information

• Product Name: (-)-(5S)-4-(4,4-difluorocyclohexyl)-2-[1-(5-{[(2S)-2,3-dihydroxypropyl]oxy}pyrimidin-2-yl)piperidin-4-yl]-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol
• Synonyms: (-)-(5S)-4-(4,4-difluorocyclohexyl)-2-[1-(5-{[(2S)-2,3-dihydroxypropyl]oxy}pyrimidin-2-yl)piperidin-4-yl]-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol
• CAS NO: 1354495-43-4
• Molecular Weight: 722.771
• Mol File: 1354495-43-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (-)-(5S)-4-(4,4-difluorocyclohexyl)-2-[1-(5-{[(2S)-2,3-dihydroxypropyl]oxy}pyrimidin-2-yl)piperidin-4-yl]-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(5S)-4-(4,4-difluorocyclohexyl)-2-[1-(5-{[(2S)-2,3-dihydroxypropyl]oxy}pyrimidin-2-yl)piperidin-4-yl]-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol(1354495-43-4)
• EPA Substance Registry System: (-)-(5S)-4-(4,4-difluorocyclohexyl)-2-[1-(5-{[(2S)-2,3-dihydroxypropyl]oxy}pyrimidin-2-yl)piperidin-4-yl]-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol(1354495-43-4)

Safety Data

• Hazardous Substances Data: 1354495-43-4(Hazardous Substances Data)

Upstream product

• 1354495-70-7 (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-2-(piperidin-4-yl)-5,6,7,8-tetrahydroquinoline 
• 1354494-81-7 (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-2-[1-(5-hydroxypyrimidin-2-yl)piperidin-4-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol 
• 1354495-94-5 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-4-(4,4-difluorocyclohexyl)-3-formyl-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-5,6,7,8-tetrahydroquinoline 
• 1354495-93-4 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-4-(4,4-difluorocyclohexyl)-3-formyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol 
• 1354495-92-3 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-3-cyano-4-(4,4-difluorocyclohexyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline 
• 1354495-91-2 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-3-cyano-4-(4,4-difluorocyclohexyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline 
• 1354495-90-1 4-(1-amino-2-cyanoethenyl)piperidin-1-carboxylic acid tert-butyl ester 
• 91419-52-2 1-tert-butoxycarbonyl-4-cyanopiperidine 
• 265108-36-9 4,4-difluorocyclohexane carboxyaldehyde 
• 178312-47-5 ethyl 4,4-difluorocyclohexane-1-carboxylate 
• 1354495-72-9 (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-2-{1-[5-(morpholin-4-yl)pyrimidin-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline 
• 1354495-44-5 (5S)-4-(4,4-difluorocyclohexyl)-2-[1-(5-{[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy}pyrimidin-2-yl)piperidin-4-yl]-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol 
• 1354495-71-8 (5S)-2-[1-(5-bromopyrimidin-2-yl)piperidin-4-yl]-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-5,6,7,8-tetrahydroquinoline 

Relevant articles and documents

ACID ADDUCT SALT OF SUBSTITUTED PYRIDINE COMPOUND

The present invention provides a salt of a substituted pyridine compound which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a salt of a compound represented by general formula (I): wherein R1 is optionally substituted alkoxy or the like.