13546-87-7Relevant academic research and scientific papers
Ruthenium-Catalyzed C-H Arylation and Alkenylation of Furfural Imines with Boronates
Siopa, Filipa,Ramis Cladera, Valérie-Anne,Afonso, Carlos Alberto Mateus,Oble, Julie,Poli, Giovanni
, p. 6101 - 6106 (2018)
A Ru0-catalyzed direct C-H arylation and alkenylation of furfural imines with aryl- or alkenyl-boronates, in the presence of benzylideneacetone as a sacrificial hydride acceptor, is disclosed. This reaction provides access, after hydrolysis, to C3-arylated or vinylated furfural derivatives, and thus valorizes these relevant building-blocks obtained from lignocellulosic biomass. This approach, involving C-H activation by a Ru0/RuII, cycle offers several advantages, notably simple, mild and neutral reaction conditions.
