135463-13-7Relevant academic research and scientific papers
Antioxidant activity of synthetic resveratrol analogs: A structure-activity insight
Calil, Natalia Oliveira,De Carvalho, Gustavo Senra Goncalves,Da Silva, Annelisa Farah,Da Silva, Adilson David,Raposo, Nadia Rezende Barbosa
, p. 676 - 679 (2012)
This study evaluated the antioxidant activity of five resveratrol analogs using the DPPH method. The molecules activity was related with their chemical structure. Besides descriptive statistics, the analysis of variance (ANOVA) followed by Tukey's post hoc test were performed (p50 value statistically different from the resveratrol (p0.001), its antioxidant activity was considered satisfactory. The other analogs (D and E), which have a 4-acid grouping in place of 4-hydroxy grouping, showed lower antioxidant activity than resveratrol (p0.001). Further studies to address possible advantages of analogs in relation to resveratrol should be conducted in order to make them feasible for therapeutic use.
