1354701-45-3

Basic information

• Product Name: (E)-(3-azido-3-methylbut-1-en-1-yl)benzene
• Synonyms: (E)-(3-azido-3-methylbut-1-en-1-yl)benzene
• CAS NO: 1354701-45-3
• Molecular Weight: 187.244
• Mol File: 1354701-45-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-(3-azido-3-methylbut-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(3-azido-3-methylbut-1-en-1-yl)benzene(1354701-45-3)
• EPA Substance Registry System: (E)-(3-azido-3-methylbut-1-en-1-yl)benzene(1354701-45-3)

Safety Data

• Hazardous Substances Data: 1354701-45-3(Hazardous Substances Data)

Upstream product

• 57132-28-2 (E)-2-methyl-4-phenylbut-3-en-2-ol 
• 100-58-3 phenylmagnesium bromide 
• 75-16-1 methylmagnesium bromide 
• 1896-62-4 (E)-benzalacetone 
• 57132-28-2 1,1-dimethyl-3-phenylprop-2-en-1-ol 

Downstream Products

• 43052-72-8 1,1-Dimethyl-3-phenyl-propylamin 
• 141983-65-5 trans-2-methyl-4-phenyl-3-buten-2-amine 

Relevant articles and documents

Direct Conversion of Aldehydes and Ketones into Azides by Sequential Nucleophilic Addition and Substitution

This report describes the direct conversion of aldehydes and ketones into alkyl azides by the addition of common organometallic reagents and tandem conversion of the resulting alkoxides without isolation of the intermediate alcohols. A wide range of aldehydes and organometallic reagents (R–Li or R–MgX) are suitable participants in this process. Additional reaction telescoping beyond azide formation is demonstrated.

Direct catalytic azidation of allylic alcohols

A direct catalytic azidation of primary, secondary, and tertiary allylic alcohols has been developed. This new azidation reaction affords the corresponding allylic azides in high to excellent yields and regioselectivities. The reaction provides straightforward access to allylic azides that are valuable intermediates in organic synthesis, including the preparation of primary amines or 1,2,3-triazole derivatives.