1354705-41-1 Usage
Structure
A pyrazole derivative with a bulky tert-butyl group and an iodine atom attached to the 4-position of the pyrazole ring.
Synonyms
4-iodo-1-(tert-butyl)pyrazole
Pharmaceutical
Potential use in the development of drugs due to the diverse biological activities of pyrazole derivatives.
Agrochemical
Potential use in the development of agrochemicals, such as pesticides or herbicides, due to the diverse biological activities of pyrazole derivatives.
Organic synthesis
Potential use as a building block for the preparation of various other chemical compounds with pyrazole moieties.
Reactivity
The specific properties and applications of 1-(tert-butyl)-4-iodo-1H-pyrazole would depend on its individual characteristics and potential reactivity in various chemical reactions.
Biological activities
Pyrazole derivatives are known for their diverse biological activities, which may include anti-inflammatory, anti-cancer, and anti-microbial properties. The exact biological activities of 1-(tert-butyl)-4-iodo-1H-pyrazole would need to be further investigated.
Check Digit Verification of cas no
The CAS Registry Mumber 1354705-41-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,4,7,0 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1354705-41:
(9*1)+(8*3)+(7*5)+(6*4)+(5*7)+(4*0)+(3*5)+(2*4)+(1*1)=151
151 % 10 = 1
So 1354705-41-1 is a valid CAS Registry Number.
1354705-41-1Relevant academic research and scientific papers
NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF
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Paragraph 2428; 2429; 2430, (2015/11/30)
A compound represented by Formula [1] (in the formula, Z1 represents N, CH, or the like; X1 represents NH or the like; R1 represents a heteroaryl group or the like; each of R2, R3, and R4 represents a hydrogen atom, a halogen atom, an alkoxy group, or the like; and R5 represents a heteroaryl group or the like) or salt thereof.
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Structure-activity relationship of the aryl region
Probst, Gary D.,Bowers, Simeon,Sealy, Jennifer M.,Stupi, Brian,Dressen, Darren,Jagodzinska, Barbara M.,Aquino, Jose,Gailunas, Andrea,Truong, Anh P.,Tso, Luke,Xu, Ying-Zi,Hom, Roy K.,John, Varghese,Tung, Jay S.,Pleiss, Michael A.,Tucker, John A.,Konradi, Andrei W.,Sham, Hing L.,Jagodzinski, Jacek,Toth, Gergely,Brecht, Eric,Yao, Nanhua,Pan, Hu,Lin, May,Artis, Dean R.,Ruslim, Lany,Bova, Michael P.,Sinha, Sukanto,Yednock, Ted A.,Gauby, Shawn,Zmolek, Wes,Quinn, Kevin P.,Sauer, John-Michael
scheme or table, p. 6034 - 6039 (2010/11/04)
The structure-activity relationship of the prime region of hydroxyethylamine BACE inhibitors is described. Variation in the aryl linker region with 5- and 6-membered heterocycles provided compounds such as 33 with improved permeability and reduced P-gp liability compared to benzyl amine analog 1.
