1354825-49-2

Upstream product

• 31519-62-7 pyrimidine-2-carboxylic acid 
• 1354824-90-0 1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide 
• 1354825-87-8 [2-(5-amino-4-cyano-3-(4-methylphenyl)-pyrazol-1-yl)-2-methyl-propyl]-carbamic acid benzyl ester 
• 1354825-85-6 N'-(2-benzyloxycarbonylamino-1,1-dimethyl-ethyl)hydrazinecarboxylic acid tert-butyl ester 
• 1354825-88-9 [2-(4-amino-3-(4-methylphenyl)-pyrazolo[3,4-d]pyrimidin-1-yl)-2-methyl-propyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

PROTEIN KINASE INHIBITORS AND METHODS OF TREATMENT

The present invention relates to chemical compounds of formula (I) and methods for their use and preparation. In particular, the invention relates to substituted pyrazolo[3,4-d]pyrimidine based compounds which can be used in treating proliferative disorders, use of these compounds in methods of therapy and the manufacture of medicaments as well as compositions containing these compounds.