1354826-75-7Relevant academic research and scientific papers
Access to L-and D-iminosugar C-glycosides from a D-gluco-derived 6-azidolactol exploiting a ring isomerization/alkylation strategy
Mondon, Martine,Fontelle, Nathalie,Desire, Jerome,Lecornue, Frederic,Guillard, Jerome,Marrot, Jerome,Bleriot, Yves
, p. 870 - 873 (2012/05/05)
A flexible synthetic access to six-membered l- and d-iminosugar C-glycosides is reported starting from the easily available 6-azido-6-deoxy-2,3, 4-tri-O-benzyl-d-glucopyranose precursor. This methodology involves a highly diastereoselective tandem ring enlargement/alkylation and a stereocontrolled ring contraction. It allows an efficient synthesis of iminosugar C-glycosides displaying structural diversity at both C-1 and C-6.
