1354906-88-9

Upstream product

• 1354910-17-0 3-[2-(4-benzyloxy-phenyl)-4,5,6,7-tetrahydro-oxazolo[4,5-c]pyridine-5-yl]-2-methyl-propionic acid t-butyl ester 
• 1354910-16-9 2-(4-benzyloxy-phenyl)-4,5,6,7-tetrahydro-oxazolo[4,5-c]pyridine 
• 1004764-45-7 2-[4-(benzyloxy)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]oxazolo[4,5-c]pyridine 
• 1354910-39-6 2-[4-(benzyloxy)phenyl]-5-methyl[1 ,3]oxazolo[4,5-c]pyridin-5-ium iodide 
• 1004764-43-5 2-[4-(benzyloxy)phenyl][1,3]oxazolo[4,5-c]pyridine 
• 6320-39-4 3-aminopyridin-4-ol 
• 1486-51-7 p-(benzyloxy)benzoic acid 

Relevant academic research and scientific papers

FUSED HETEROCYCLIC DERIVATIVES AS S1P MODULATORS

The present invention relates to a fused heterocyclic derivative of the formula (I) The variables R1-R4, z, A, Q, X and Y are as defined in the claims. The following heterocycles are exemplified substructures of formula (I): The compounds of formula (I) are modulators of the S1P receptor (Sphingosine-1-phosphate receptor), More specifically, they are agonists of S1P5. The compounds have therapeutic use in treatment of cognitive disorders, age-relate cognitive decline and dementia.