135508-47-3

Upstream product

• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 100777-91-1 (2S)-2,3-O-isopropylideneglyceraldehyde N-benzylimine 
• 100-46-9 benzylamine 
• 131319-74-9 (R)-2,3-di-O-isoproylideneglyceraldehyde N-benzylimine 
• 213480-18-3 (3R,4S)-1-benzyl-4-[(1S)-3,3-dimethyl-2,4-dioxacyclopentane-1-yl]-3-acetoxyazetidin-2-one 
• 143159-97-1 (+)-(3R,4S)-cis-1-benzyl-3-benzyloxy-4-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-azetidinone 

Downstream Products

• 87408-17-1 (R)-1-Benzyl-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-azetidin-2-one 
• 87408-18-2 (R)-1-Benzyl-4-((S)-1,2-dihydroxy-ethyl)-azetidin-2-one 
• 87408-21-7 (S)-1-Benzyl-4-(2-hydroxy-ethyl)-azetidin-2-one 
• 869283-89-6 Methanesulfonic acid (2S,3R)-1-benzyl-2-((S)-1,2-dihydroxy-ethyl)-4-oxo-azetidin-3-yl ester 
• 869283-98-7 (3R,4S)-1-benzyl-4-hydroxymethyl-3-mesyloxyazetidin-2-one 
• 869283-95-4 (3R,4R)-1-benzyl-4-formyl-3-mesyloxyazetidin-2-one 
• 301532-94-5 (2R,3R)-3-Benzylamino-3-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-propane-1,2-diol 
• 160527-47-9 (S)-3-Benzyl-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-oxazolidine-2,5-dione 
• 135508-48-4 Dithiocarbonic acid O-[(2S,3R)-1-benzyl-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-4-oxo-azetidin-3-yl] ester S-methyl ester 

Relevant academic research and scientific papers

Stereospecific novel glycosylation of hydroxy β-lactams via iodine-catalyzed reaction: A new method for optical resolution

Glycosylation of racemic and optically active α-hydroxy β-lactams by reaction with a few glycal derivatives in the presence of catalytic amounts of iodine has provided stereospecific formation of α-glycosides. This method has been extended for the prepara

An efficient synthesis of 2,3-aziridino-γ-lactones from azetidin-2-ones

An efficient synthesis of enantiopure 2,3-aziridino-γ-lactones from azetidin-2-ones is described. Acid-catalyzed tandem intramolecular azetidinone ring opening followed by aziridine ring formation via elimination of a mesylate group is the key step in thi

Polyhydroxy amino acid derivatives via β-lactams using enantiospecific approaches and microwave techniques

Enantiospecific synthesis has been developed for α-hydroxy β-lactams of predictable absolute configuration starting with readily available carbohydrates. Stereospecific approaches and microwave assisted chemical reactions have been utilized for the prepar

Practical synthesis of α-amino acid N-carboxy anhydrides of polyhydroxylated α-amino acids from β-lactam frameworks. Model studies toward the synthesis of directly linked peptidyl nucleoside antibiotics

A straightforward method for the synthesis of polyhydroxylated α-amino acid N-carboxy anhydrides (NCAs) is described as the means by which short peptide segments comprised of a polyhydroxylated chain are easily affordable. The entire sequence lies in the

MICROWAVE-INDUCED ORGANIC REACTION ENHANCEMENT CHEMISTRY. 4 CONVENIENT SYNTHESIS OF ENANTIOPURE α-HYDROXY-β-LACTAMS

A convenient and rapid synthesis of enantiopure α-hydroxy-β-lactams using microwave-induced organic reaction enhancement chemistry has been developed.Reactions in domestic microwave ovens, which are very convenient and economical for small scale work in research or teaching laboratories, can also be conducted on a preparative scale of 100 - 500 g in simple beakers or flasks. Key Words: α-Hydroxy-β-lactams, microwave-induced organic reactions, enantiospecific synthesis