135513-99-4

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 135514-06-6 1,1-dimethylethyl 3-(4-bromophenyl)-2-methylene-3-oxopropanoate 
• 59082-30-3 (Z)-2-p-Bromobenzyliden-1-indanon 
• 5706-19-4 (E)-2-(4-bromobenzylidene)-2,3-dihydro-1H-inden-1-one 
• 951695-76-4 C₁₆H₁₉O₄Br 
• 951695-20-8 t-butyl 2-[(dimethylphosphoryl)methyl]-3-(4-bromophenyl)-2-propenoate 
• 951695-42-4 2-[(dimethylphosphoryl)methyl]-3-(4-bromophenyl)-2-propenoic acid 
• 135514-15-7 1,1-dimethylethyl 6-(4-bromophenyl)-2,3,3a,7a-tetrahydro-4H-furo<2,3-b>pyran-5-carboxylate 
• 1312803-50-1 (S)-tert-butyl 3-(4-bromophenyl)-4,4,4-trifluoro-2-methylenebutanoate 
• 1571082-54-6 tert-butyl 2-[(4-bromophenyl)fluoromethyl]acrylate 
• 1312803-44-3 tert-butyl 2-((4-bromophenyl)(tert-butoxycarbonyloxy)methyl)acrylate 

Relevant academic research and scientific papers

Asymmetric synthesis of 2-alkyl-3-phosphonopropanoic acids via P - C bond formation and hydrogenation

Allylic acetates, formed by the acetylation of Baylis Hillman adducts, undergo addition of phosphorus nucleophiles to give stereoselectively the Z-unsaturated esters. TFA cleavage of the fert-butyl ester and asymmetric hydrogenation of the unsaturated aci

Unprecedented E-stereoselectivity on the sigmatropic Hurd-Claisen rearrangement of Morita-Baylis-Hillman adducts: A joint experimental-theoretical study

Herein we report the first systematic investigation of the tandem mercury(ii) catalysed transvinylation/Hurd-Claisen rearrangement of MBH adducts derived from alkyl acrylates. This is the first report of E-selectivity for MBH adducts with alkyl side chain

Direct Synthesis of Dihydropyrrolo[2,1-a]Isoquinolines through FeCl3 Promoted Oxidative Aromatization

We have developed a straightforward FeCl3 promoted synthesis of dihydropyrrolo[2,1-a]isoquinolines through formal (3+2) cycloaddition/oxidative aromatization cascade of dihydroisoquinoline with Morita-Baylis-Hillman carbonates (up to 96% yield)

The Baylis-Hillman reaction: Rate acceleration in silica gel solid phase medium

Remarkable rate acceleration in the Baylis-Hillman reaction of aromatic aldehydes with acrylates, particularly tertbutyl acrylate, in silica gel solid phase medium has been described.

Preparation and Selected Reactions of t-Butyl 2-Methylene-3-oxoalkanoates

The title class of 1,1-diactivated ethylenes has been prepared in two steps from aldehydes and t-butyl acrylate by (i) DABCO-catalyzed coupling to give t-butyl 2-(hydroxyalkyl)-2-propenoates 11 and (ii) low-temperature Jones oxidation, followed by swift work up at low temperature.The resulting butyl 2-methylene-3-oxoalkanoates 12 are stabilized by sterically demanding and also by aromatic groups R.For primary unhindered alkyl groups, stability is low.The compounds enter into Michael reactions, hetero Diels-Alder additions with enol ethers, and self-dimerization.Key Words: Ethylenes, 2,2-diactivated/ Michael acceptors/ 1-Oxa-1,3-butadienes/Hetero Diels-Alder reaction