951695-76-4

Upstream product

• 135513-99-4 1,1-dimethylethyl 3-(4-bromophenyl)-3-hydroxy-2-methylene-propanoate 
• 75-36-5 acetyl chloride 
• 1663-39-4 tert-Butyl acrylate 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 951695-20-8 t-butyl 2-[(dimethylphosphoryl)methyl]-3-(4-bromophenyl)-2-propenoate 
• 1312803-11-4 tert-butyl 3-(4-bromophenyl)-4,4,4-trifluoro-2-methylenebutanoate 
• 1022901-48-9 di-tert-butyl 2,6-di[(E)-4-bromobenzylidene]-4-cyano-4-phenyl-1,7-heptanedioate 
• 951695-42-4 2-[(dimethylphosphoryl)methyl]-3-(4-bromophenyl)-2-propenoic acid 

Relevant academic research and scientific papers

Asymmetric synthesis of 2-alkyl-3-phosphonopropanoic acids via P - C bond formation and hydrogenation

Allylic acetates, formed by the acetylation of Baylis Hillman adducts, undergo addition of phosphorus nucleophiles to give stereoselectively the Z-unsaturated esters. TFA cleavage of the fert-butyl ester and asymmetric hydrogenation of the unsaturated aci