1355331-87-1

Upstream product

• 87905-98-4 5-<(benzyloxycarbonyl)amino>pentanol 
• 149707-75-5 2,3,4,6-tetra-O-benzoyl-1-O-trichloroacetimidoyl-α-D-galactopyranose 
• 98-88-4 benzoyl chloride 
• 627466-84-6 2,3,4,6-tetra-O-benzoyl-D-galactose 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-α-D-galactopyranoside 

Downstream Products

• 160242-89-7 5-(N-benzyloxycarbonyl)aminopentyl β-D-galactopyranoside 

Relevant academic research and scientific papers

Mitochondrial affinity of guanidine-rich molecular transporters built on monosaccharide scaffolds: Stereochemistry and lipophilicity

We synthesized eight G8 molecular transporters (MTs) based on 4 different monosaccharide scaffolds, and studied their biological properties with a special focus on possible mitochondrial targeting and tissue selectivity. The mitochondrial affinity of these MTs was found to be clearly related to the scaffold stereochemistry and also tenuously with the lipophilicity. It may be suggested that in the practical delivery strategy of drugs for the brain and mitochondrial diseases the BBB permeability and mitochondrial affinity should be considered as key parameters, and that an enhanced mitochondrial affinity appears possible by further research on the structure-property relationship of guanidine-rich molecular transporters.