1355450-12-2

Basic information

• Product Name: tris(1-isoquinolylmethyl)amine
• Synonyms: tris(1-isoquinolylmethyl)amine
• CAS NO: 1355450-12-2
• Molecular Weight: 440.547
• Mol File: 1355450-12-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tris(1-isoquinolylmethyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: tris(1-isoquinolylmethyl)amine(1355450-12-2)
• EPA Substance Registry System: tris(1-isoquinolylmethyl)amine(1355450-12-2)

Safety Data

• Hazardous Substances Data: 1355450-12-2(Hazardous Substances Data)

Upstream product

• 27311-65-5 1-chloromethyl-isoquinoline 
• 40615-08-5 [(isoquinolin-1-yl)methyl]amine 

Relevant articles and documents

Zinc-specific fluorescent response of tris(isoquinolylmethyl)amines (isoTQAs)

Isoquinoline-based tetradentate ligands with C3-symmetry, tris(1- or 3-isoquinolylmethyl)amine (1- or 3-isoTQA), have been prepared and their zinc-induced fluorescence enhancement was investigated. Upon excitation at 324 nm, 1-isoTQA shows very weak fluorescence (β = ～0.003) in DMF/H2O (1/1) solution. In the presence of zinc ion, 1-isoTQA exhibits fluorescence increase (β = 0.041) at 359 and 470 nm. This fluorescence enhancement at 470 nm is specific for zinc. However, 3-isoTQA exhibited a smaller fluorescence enhancement upon zinc complexation (β = 0.017, λem = 360 and 464 nm) compared with 1-isoTQA. Crystal structures of zinc complexes of isoTQAs demonstrate the diminished steric crowding and shorter Zn-Naromatic distances compared with isoTQENs (N,N,N′,N′-tetrakis(isoquinolylmethyl)ethylenediamines) leads to a higher fluorescent response toward zinc relative to cadmium.