13555-38-9

Upstream product

• 142-04-1 aniline hydrochloride 
• 62-53-3 aniline 
• 98-86-2 acetophenone 

Downstream Products

• 1255766-42-7 N,N'-[(1-phenylethylidene)di-4,1-phenylene]bis[2-(1-pyrrolidinyl)acetamide] 
• 1255767-98-6 N,N'-[(1-phenylethylidene)di-4,1-phenylene]bis(2-bromoacetamide) 
• 1293372-84-5 4,4'-(1-phenylethane-1,1-diyl)bis(N,N-bis(3-(biphenyl-3-yl)phenyl)aniline) 
• 1360473-62-6 C₃₂H₂₆N₄ 

Relevant academic research and scientific papers

NOVEL (POLY)AMINE COMPOUND, RESIN AND CURED PRODUCT

A (poly)amine compound represented by the following formula (0): wherein RX is a 2nA-valent group having 1 to 70 carbon atoms or a single bond;each R1A is independently any of an alkyl group having 1 to 30 carbon atoms and optionally having a substituent, an aryl group having 6 to 30 carbon atoms and optionally having a substituent, a crosslinking group having 2 to 30 carbon atoms and optionally having a substituent, an alkoxy group having 1 to 30 carbon atoms and optionally having a substituent, a halogen atom, a nitro group, an amino group having 0 to 30 carbon atoms and optionally having a substituent, a carboxyl group, a thiol group and a hydroxy group, wherein when R1A is any of the alkyl group, the aryl group, the crosslinking group and the alkoxy group, R1A optionally contains at least one bond selected from the group consisting of an ether bond, a ketone bond and an ester bond, and at least one R1A is an amino group having 0 to 30 carbon atoms and optionally having a substituent;X is an oxygen atom or a sulfur atom, or X is optionally absent;each R independently represents any of a benzene ring, a biphenyl ring, a naphthalene ring, an anthracene ring and a pyrene ring;each m is independently an integer of 0 to 9, wherein at least one m is an integer of 1 to 9; andnA is an integer of 1 to 4.

Induction of point chirality by E/Z photoisomerization

Shining a light on it: E/Z photoisomerization generates an asymmetric center and the corresponding separable enantiomers in an azobenzene-based prochiral molecule. This asymmetric center is formed by light-induced changes to the substituents on the centra

Synthesis of GN8 derivatives and evaluation of their antiprion activity in TSE-infected cells

A series of GN8 derivatives were synthesized from various diamines, carboxylic acid derivatives, and nitrogen nucleophiles, and their antiprion activity was tested in TSE-infected mouse neuronal cells. We found that two ethylenediamine units, hydrophobic substituents on the nitrogen atoms, and the diphenylmethane scaffold were essential structural features responsible for the activity. Seven derivatives bearing substituents at the benzylic position exhibited an improved antiprion activity with the IC50 values of 0.51-0.83 μM. Conformational analysis of model compounds suggested that the introduction of the substituent at the benzylic position restricted the conformational variability of the diphenylmethane unit.