135556-98-8

Basic information

• Product Name: (3S,4R)-3-((R)-(1-(tert-butyldimethylsilyl)oxy)ethyl)-4-((1S)-2-oxocyclohexyl)-azetidine-2-one
• Synonyms: (3S,4R)-3-((R)-(1-(tert-butyldimethylsilyl)oxy)ethyl)-4-((1S)-2-oxocyclohexyl)-azetidine-2-one
• CAS NO: 135556-98-8
• Molecular Weight: 325.524
• Mol File: 135556-98-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (3S,4R)-3-((R)-(1-(tert-butyldimethylsilyl)oxy)ethyl)-4-((1S)-2-oxocyclohexyl)-azetidine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-3-((R)-(1-(tert-butyldimethylsilyl)oxy)ethyl)-4-((1S)-2-oxocyclohexyl)-azetidine-2-one(135556-98-8)
• EPA Substance Registry System: (3S,4R)-3-((R)-(1-(tert-butyldimethylsilyl)oxy)ethyl)-4-((1S)-2-oxocyclohexyl)-azetidine-2-one(135556-98-8)

Safety Data

• Hazardous Substances Data: 135556-98-8(Hazardous Substances Data)

Upstream product

• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 86978-81-6 (3R,4R)-4-acetoxy-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-1-trimethylsilyl-2-azetidinone 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 
• 85281-73-8 (3S,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)-ethyl]-4-phenylthio-2-azetidinone 
• 144069-72-7 (3S,4R)-3-<(1R)-1-(tert-Butyldimethylsiloxy)ethyl>-4-phenylsulfinylazetidin-2-one 
• 5453-93-0 allyl 2-oxocyclohexane-1-carboxylate 
• 670-80-4 4-cyclohexen-1-ylmorpholine 

Downstream Products

• 141040-90-6 (3S,4R)-3-<(1R)-1-(tert-Butyldimethylsilyloxy)ethyl>-4-<(3'R)-cyclohex-1'-en-3'-yl>azetidin-2-one 
• 136375-53-6 [(3S,4R)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-oxo-4-((S)-2-oxo-cyclohexyl)-azetidin-1-yl]-oxo-acetic acid allyl ester 

Relevant articles and documents

Design, synthesis and bioactivity evaluation of tribactam beta lactamase inhibitors.

Known carbapenem compounds with inhibitory effect towards beta-lactamase enzymes are formed from bicyclical beta lactam structural scaffolds. On the basis of results from theoretical computational methods and molecular modelling we have designed and devel

Synthesis and NMR studies of key intermediates to a new class of β-lactam: The trinems

An efficient synthesis of the four isomeric epoxides 4a-d, key compounds to the trinem ring system, starting from (3R,4R,1′R)-(+)-4-acetoxy-3-[1′-(tert-butyldimethylsilyloxy)ethyl] azetidin-2-one 6a is described. All the intermediates have been characteri

Chemistry of O-Silylated Ketene Acetals: An Efficient Synthesis of Carbapenem and 1β-Methylcarbapenem Intermediates

3-(1-tert-Butyldimethylsiloxyethyl)-4-phenylsulfinylazetidin-2-one reacted smoothly with various types of O-silylated ketene acetals and silylated enol ethers in the presence of a catalytic amount of zinc iodide to give the corresponding trans-4-substitut