1355611-39-0

Basic information

• Product Name: (S)-ethyl 2-((S)-1-(benzyloxycarbonylamino)-2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-thioxoethyl)but-3-enoate
• Synonyms: (S)-ethyl 2-((S)-1-(benzyloxycarbonylamino)-2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-thioxoethyl)but-3-enoate
• CAS NO: 1355611-39-0
• Molecular Weight: 418.557
• Mol File: 1355611-39-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-ethyl 2-((S)-1-(benzyloxycarbonylamino)-2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-thioxoethyl)but-3-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-ethyl 2-((S)-1-(benzyloxycarbonylamino)-2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-thioxoethyl)but-3-enoate(1355611-39-0)
• EPA Substance Registry System: (S)-ethyl 2-((S)-1-(benzyloxycarbonylamino)-2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-thioxoethyl)but-3-enoate(1355611-39-0)

Safety Data

• Hazardous Substances Data: 1355611-39-0(Hazardous Substances Data)

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 62617-70-3 (2R,5R)-2,5-dimethylpyrrolidine 
• 6065-32-3 4-bromocrotonic ethyl ester 
• 1355611-20-9 benzyl (2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-thioxoethyl)-carbamate 
• 953787-28-5 benzyl 2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)-2-oxoethylcarbamate 

Downstream Products

• 1355611-68-5 (2S,3S)-2-(benzyloxycarbonylamino)-3-(ethoxycarbonyl)pent-4-enoic acid 

Relevant articles and documents

Thio-Claisen rearrangement used in preparing anti-β-functionalized γ,δ-unsaturated amino acids: Scope and limitations

Multifunctionalized amino acids, especially amino acids with unsaturation, are important, demanding building blocks in peptide chemistry. Here we present a summary of our most recent study using the thio-Claisen rearrangement for the synthesis of anti-β-f