135562-24-2

Basic information

• Product Name: (+)-4-bromo-15-(p-toluenesulfonyl)<2.2>paracyclophane
• Synonyms: (+)-4-bromo-15-(p-toluenesulfonyl)<2.2>paracyclophane
• CAS NO: 135562-24-2
• Molecular Weight: 441.389
• Mol File: 135562-24-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+)-4-bromo-15-(p-toluenesulfonyl)<2.2>paracyclophane(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-4-bromo-15-(p-toluenesulfonyl)<2.2>paracyclophane(135562-24-2)
• EPA Substance Registry System: (+)-4-bromo-15-(p-toluenesulfonyl)<2.2>paracyclophane(135562-24-2)

Safety Data

• Hazardous Substances Data: 135562-24-2(Hazardous Substances Data)

Upstream product

• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 1908-61-8 4-bromo[2.2]paracyclophane 
• 135562-22-0 (-)-(R_P,S_S)-4-(p-toluenesulfinyl)<2.2>paracyclophane 

Downstream Products

• 135562-18-4 4-(geranylseleno)-15-(p-toluenesulfonyl)<2.2>paracyclophane 
• 135562-15-1 bis(15-(p-toluenesulfonyl)<2.2>paracyclophan-4-yl) diselenide 

Relevant articles and documents

Towards a flexible strategy for the synthesis of enantiomerically pure [2.2]paracyclophane derivatives: The chemistry of 4-tolylsulfinyl[2.2] paracyclophane

The use of enantiomerically enriched 4-tolylsulfinyl[2.2]paracyclophane as a precursor to a variety of mono- and di-substituted [2.2]paracyclophane derivatives is described. The goal of our research is to develop a single general precursor that permits the synthesis of the most common [2.2]paracyclophane substitution patterns. The chemistry of two diastereoisomers of 4-tolylsulfinyl[2.2]paracyclophane has been explored and it facilitates the synthesis of enantiomerically enriched 4-substituted and 4,13-disubstituted [2.2]paracyclophanes. Directed lithiations result in an unusual cyclisation reaction. Whilst the tolyl group cannot realise our goal, the chemistry outlined acts as a successful proof of concept.