1355700-62-7Relevant academic research and scientific papers
Synthesis of Isothiochroman-3-ones via Metal-Free Oxidative Cyclization of Alkynyl Thioethers
Zhang, Ying-Qi,Zhu, Xin-Qi,Chen, Yang-Bo,Tan, Tong-De,Yang, Ming-Yang,Ye, Long-Wu
, p. 7721 - 7725 (2018)
A novel Br?nsted acid-catalyzed oxidative C-H functionalization of alkynyl thioethers has been developed. This method allows the practical synthesis of valuable isothiochroman-3-ones in mostly moderate to good yields under mild reaction conditions and features a broad substrate scope and wide functional group tolerance. Moreover, this metal-free oxidation can also be used to promote formal N-H insertion involving an unexpected 1,2-sulfur migration, affording useful 1,4-benzothiazin-3-ones.
Lewis acid-promoted hydrofluorination of alkynyl sulfides to generate α-fluorovinyl thioethers
Bello, Davide,O'Hagan, David
supporting information, p. 1902 - 1909 (2016/04/10)
A new method for the preparation of α-fluorovinyl thioethers is reported which involves the hydrofluorination of alkynyl sulfides with 3HF·Et3N, a process that requires Lewis acid activation using BF3·Et2O and TiF4/s
A one-pot synthesis of alkynyl sulfides from terminal alkynes
Zheng, Weixin,Zheng, Fenfen,Hong, Ya,Hu, Linfeng
experimental part, p. 105 - 110 (2012/03/26)
A one-pot synthesis of alkynyl sulfide from terminal alkyne has been reported via lithiation of the alkyne, oxidative addition of sulfur, consecutively followed by the nucleophilic substitution of lithium alkynyl thiolate to various halides.
