135574-62-8

Basic information

• Product Name: (2S,3R,4S)-2-(hydroxymethyl)-4-[(11R,12R)-11-hydroxy-12-methyltetradecyl]azetidin-3-ol
• CAS NO: 135574-62-8
• Molecular Formula: C₁₉H₃₉NO₃
• Molecular Weight: 329.5179
• Mol File: 135574-62-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 481.8°C at 760 mmHg
• Flash Point: 84.1°C
• Density: 0.989g/cm³
• Vapor Pressure: 2.62E-11mmHg at 25°C
• Refractive Index: 1.488
• CAS DataBase Reference: (2S,3R,4S)-2-(hydroxymethyl)-4-[(11R,12R)-11-hydroxy-12-methyltetradecyl]azetidin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4S)-2-(hydroxymethyl)-4-[(11R,12R)-11-hydroxy-12-methyltetradecyl]azetidin-3-ol(135574-62-8)
• EPA Substance Registry System: (2S,3R,4S)-2-(hydroxymethyl)-4-[(11R,12R)-11-hydroxy-12-methyltetradecyl]azetidin-3-ol(135574-62-8)

Safety Data

• Hazardous Substances Data: 135574-62-8(Hazardous Substances Data)

Upstream product

• 78260-12-5 (2S,3R)-3-ethenyloxirane-2-methanol 
• 187100-44-3 (2S,3S,4R,15S,16S)-1,3,15-Tris-tert-butyldimethylsilyloxy-16-methyl-2-p-tolylsulfonylaminooctadecan-4-ol 
• 187100-43-2 (2S,3S,4R,5S,15S,16S)-1,3,15-Tris-tert-butyldimethylsilyloxy-4,5-epoxy-16-methyl-2-p-tolylsulfonylaminooctadecane 
• 171017-02-0 (12R,13S)-13-Methylpentadec-1-yn-12-ol 
• 187100-34-1 (12S,13S)-13-Methylpentadec-1-yn-12-ol 
• 187100-35-2 (12S,13S)-12-tert-Butyldimethylsilyloxy-13-methylpentadec-1-yne 
• 187100-39-6 (2S,3R,15S,16S,4E)-2-Amino-1,3,15-tris-tert-butyldimethylsilyloxy-16-methyloctadec-4-ene 
• 187100-36-3 tert-Butyl (4S)-4-<(1'R,13'S,14'S)-13'-tert-butyldimethylsilyloxy-1'-hydroxy-14'-methylhexadec-2'-ynyl>-2,2-dimethyloxazolidine-3-carboxylate 
• 187100-46-5 (2S,3R,4S,11'S,12'S)-3-tert-Butyldimethylsilyloxy-2-tert-butyldimethylsilyloxymethyl-4-(11'-tert-butyldimethylsilyloxy-12'-methyltetradecyl)-N-p-tolylsulfonylazetidine 
• 187100-40-9 (2S,3R,15S,16S,4E)-1,3,15-Tris-tert-butyldimethylsilyloxy-16-methyl-2-p-tolylsulfonylaminooctadec-4-ene 
• 922-65-6 divinylcarbinol 
• 187100-38-5 (E)-(2S,3R,15S,16S)-2-Amino-15-(tert-butyl-dimethyl-silanyloxy)-16-methyl-octadec-4-ene-1,3-diol 
• 171017-10-0 (3S,4R)-3-Methylpentadec-6-yn-4-ol 
• 187100-33-0 3,5-Dinitro-benzoic acid (S)-1-((S)-sec-butyl)-dodec-11-ynyl ester 

Relevant articles and documents

Novel enantioselective synthesis of penaresidin A and Allo-penaresidin A via the construction of a highly functionalized azetidine

A new and highly enantioselective synthesis of penaresidin A has been achieved via the construction of a highly functionalized azetidine with the requisite stereogenic centers, which can also be regarded as an advanced intermediate for the synthesis of penaresidin B and penazetidine A.

Synthesis of penaresidin A, an azetidine alkaloid with actomyosin ATPase-activating property

Three stereoisomers of pentaresidin A (1) an azetidine alkaloid isolated from the Okinawan marine sponge Penares sp., were synthesized. The natural penaresidin A must be either (2S,3R,4S,15S,16S)- or (2S,3R,4S,15R,16R)-1.