13558-65-1

Basic information

• Product Name: N-(4-acetylphenyl)-N'-phenylthiourea
• Synonyms: N-(4-acetylphenyl)-N'-phenylthiourea;1-(4-acetylphenyl)-3-phenylthiourea
• CAS NO: 13558-65-1
• Molecular Formula: C₁₅H₁₄N₂OS
• Molecular Weight: 270.34946
• Mol File: 13558-65-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 155-157 °C
• Boiling Point: 422.3±47.0 °C(Predicted)
• Appearance: /
• Density: 1.291±0.06 g/cm3(Predicted)
• PKA: 12.01±0.70(Predicted)
• CAS DataBase Reference: N-(4-acetylphenyl)-N'-phenylthiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-acetylphenyl)-N'-phenylthiourea(13558-65-1)
• EPA Substance Registry System: N-(4-acetylphenyl)-N'-phenylthiourea(13558-65-1)

Safety Data

• Hazardous Substances Data: 13558-65-1(Hazardous Substances Data)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 99-92-3 p-aminobenzophenone 

Downstream Products

• 1350728-52-7 4-methoxy-4'-(phenylthiourenyl)chalcone 
• 1350728-50-5 4-chloro-4'-(phenylthiourenyl)chalcone 
• 62731-26-4 N-[4-(1-hydroxyimino-ethyl)-phenyl]-N'-phenyl-thiourea 

Relevant articles and documents

Evaluation of new chalcone derivatives as polyphenol oxidase inhibitors

A newly series of 4-(phenylurenyl)chalcone (4a-j) and 4′- (phenylurenyl/thiourenyl)chalcone (9a-l) derivatives were synthesized and their inhibitory effects on the diphenolase activity of banana tyrosinase were evaluated. Tyrosinase has been purified from banana on an affinity gel comprised of Sepharose 4B-l-tyrosine-p-aminobenzoic acid. The result showed that 4a-j inhibited the PPO enzyme activity. Conversely, 9a-h and 9i-l showed activator effect on tyrosinase enzyme activity.