135586-55-9

Upstream product

• 83-33-0 inden-1-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 5706-14-9 2-[(E)-4-methoxyphenylmethylidene]-1-indanone 
• 108-24-7 acetic anhydride 
• 124996-01-6 (E)-2-(4-hydroxybenzylidene)-2,3-dihydro-1H-inden-1-one 

Relevant academic research and scientific papers

Light-enabled, AlCl3-catalyzed regioselective intramolecular nucleophilic addition of non-nucleophilic alkyls to alkynes

Light-enabled, AlCl3-catalyzed regioselective intramolecular nucleophilic cyclization of alkynes using non-nucleophilic alkyls as the nucleophile is reported. Upon photoexcitation, o-alkylphenyl alkynyl ketones can be transferred into (E)-photoenols. Thus, a nucleophilic methylene is formed from the non-nucleophilic alkyl. An AlCl3 catalyst can stabilize the (E)-photoenol intermediate and facilitate further intramolecular nucleophilic cyclization. DFT calculations indicated that the AlCl3-catalyzed cyclization is the regioselectivity determining step.

Synthesis of 3,3a-trans/cis-2-phenyl/acetyl-3-aryl-tetrahydroindeno/naphtho-and hexahydrobenzocycloheptapyrazoles as antiimplantation agents

Reaction of benzocycloalkanones (1-3 and 24) and araldehydes (4-6) gives the arylideno-alkanones (7-12, 25 and 26) of which 11 and 12 on alkylation and acetylation afford alkyl ethers (13, 14 and 17) and acetates (15 and 16) respectively.Condensation of a