135587-64-3Relevant academic research and scientific papers
Organocatalytic asymmetric Sulfa-Michael addition of thiols to 4,4,4-trifluorocrotonates
Dong, Xiu-Qin,Fang, Xin,Wang, Chun-Jiang
supporting information; experimental part, p. 4426 - 4429 (2011/10/08)
The first asymmetric sulfa-Michael addition of thiols to 4,4,4-trifluorocrotonates for the construction of a stereogenic center bearing a unique trifluoromethyl group and a sulfur atom has been achieved in high yields and excellent enantioselectivities wi
A novel chemoenzymatic enantioselective synthesis of some clinically effective CNS drugs and related compounds
Kumar, Ashok,Ner, D H,Dike, Suneel
, p. 803 - 809 (2007/10/02)
We have demonstrated in this study a novel route for the synthesis of benzothiopyran and benzothiazepin ring systems along with the synthesis of optically pure, clinically effective drugs tomoxetine, fluoxetine and thiazesim.
