1355966-30-1

Basic information

• Product Name: N-methoxy-N,3-dimethyl-2-nitrobenzamide
• Synonyms: N-methoxy-N,3-dimethyl-2-nitrobenzamide
• CAS NO: 1355966-30-1
• Molecular Weight: 224.216
• Mol File: 1355966-30-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-methoxy-N,3-dimethyl-2-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methoxy-N,3-dimethyl-2-nitrobenzamide(1355966-30-1)
• EPA Substance Registry System: N-methoxy-N,3-dimethyl-2-nitrobenzamide(1355966-30-1)

Safety Data

• Hazardous Substances Data: 1355966-30-1(Hazardous Substances Data)

Upstream product

• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 50424-93-6 3-methyl-2-nitrobenzoyl chloride 

Downstream Products

• 1584647-85-7 (2R,3S)-N-((3S)-5-(3-fluorophenyl)-9-(hydroxymethyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-2,3-bis(3,3,3-trifluoropropyl)succinamide 
• 1584648-44-1 3-amino-5-(3-fluorophenyl)-9-(hydroxymethyl)-1H-benzo[e][1,4]diazepin-2(3H)-one 
• 1584648-46-3 (2S,3R)-6,6,6-trifluoro-3-((5-(3-fluorophenyl)-9-(hydroxymethyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamoyl)-2-(3,3,3-trifluoropropyl)hexanoic acid 
• 1584648-45-2 (2S,3R)-tert-butyl 6,6,6-trifluoro-3-((5-(3-fluorophenyl)-9-(hydroxymethyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamoyl)-2-(3,3,3-trifluoropropyl)hexanoate 
• 1584648-43-0 benzyl (9-(((tert-butyldimethylsilyl)oxy)methyl)-5-(3-fluorophenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamate 
• 1584648-42-9 (2-amino-3-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)(3-fluorophenyl)methanone 
• 1584648-41-8 2-amino-3-(((tert-butyldimethylsilyl)oxy)methyl)-N-methoxy-N-methylbenzamide 
• 1584648-40-7 3-(((tert-butyldimethylsilyl)oxy)methyl)-N-methoxy-N-methyl-2-nitrobenzamide 
• 1584648-39-4 3-(hydroxymethyl)-N-methoxy-N-methyl-2-nitrobenzamide 
• 1355967-16-6 C₁₆H₂₂N₄O₂ 
• 1355967-14-4 C₁₆H₂₀N₄O₄ 
• 1355967-12-2 C₁₉H₂₆N₂O₅Si 
• 1355967-10-0 C₁₆H₂₃N₃O₆ 
• 1355967-08-6 C₁₁H₁₅N₃O₄ 

Relevant articles and documents

BIS(FLUOROALKYL)-1,4-BENZODIAZEPINONE COMPOUNDS AND PRODRUGS THEREOF

Disclosed are compounds of Formula (I) and/or salts thereof: wherein R1 is —CH2CH2CF3; R2 is —CH2CH2CF3 or —CH2CH2CH2CF3; R3 is H, —CH3, or Rx; R4 is H or Ry; Ring A is phenyl or pyridinyl; and Rx, Ry, Ra, Rb, y, and z are defined herein. Also disclosed are methods of using such compounds to inhibit the Notch receptor, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as cancer; or as prodrugs of such compounds.