135616-17-0

Basic information

• Product Name: 5-Methyl-5-phenyl-cyclohex-1-enecarboxylic acid 4-methyl-2-thioxo-thiazol-3-yl ester
• Synonyms: 5-Methyl-5-phenyl-cyclohex-1-enecarboxylic acid 4-methyl-2-thioxo-thiazol-3-yl ester
• CAS NO: 135616-17-0
• Molecular Weight: 345.486
• Mol File: 135616-17-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Methyl-5-phenyl-cyclohex-1-enecarboxylic acid 4-methyl-2-thioxo-thiazol-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-5-phenyl-cyclohex-1-enecarboxylic acid 4-methyl-2-thioxo-thiazol-3-yl ester(135616-17-0)
• EPA Substance Registry System: 5-Methyl-5-phenyl-cyclohex-1-enecarboxylic acid 4-methyl-2-thioxo-thiazol-3-yl ester(135616-17-0)

Safety Data

• Hazardous Substances Data: 135616-17-0(Hazardous Substances Data)

Upstream product

• 49762-08-5 3-hydroxy-4-methylthiazole-2(3H)-thione 
• 135616-27-2 5-methyl-5-phenylcyclohexene-1-carboxylic acid 

Downstream Products

• 135615-91-7 (3-bromo-1-methyl-3-cyclohexen-1-yl)benzene 

Relevant articles and documents

Regioselective Conversion of Cycloalkanones to Vinyl Bromide with 1,2-Functionality Transposition. A General Strategem

Cyclic β-keto esters, available by regioselective acylation of cycloalkanone enolates, are rapidly transformed to α,β-unsaturated acids.This functionality transposition allows the derived 3-hydroxy-4-methylthiazole-2-(3H)-thione derivatives to serve as precursors to synthetically useful vinyl bromides.The process involves heating the hydroxamate ester with AIBN in bromotrichloromethane solution.Alkylative and ring contractive variants of the methodology are highlighted.The short sequence makes available precursors to vinyl anions that are not otherwise conveniently accessible.