1356266-06-2

Basic information

• Product Name: (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate
• Synonyms: (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate
• CAS NO: 1356266-06-2
• Molecular Weight: 355.414
• Mol File: 1356266-06-2.mol

Chemical Properties

• CAS DataBase Reference: (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate(1356266-06-2)
• EPA Substance Registry System: (E)-ethyl 2-(4,4-dioxido-8b-phenyl-1H-azeto[1,2-b]benzo[d]isothiazol-2-(8bH)-ylidene)acetate(1356266-06-2)

Safety Data

• Hazardous Substances Data: 1356266-06-2(Hazardous Substances Data)

Upstream product

• 53440-57-6 3-phenylbenzo[d]isothiazole-1,1-dioxide 
• 14369-81-4 ethyl 2,3-butadienoate 

Relevant articles and documents

A Scaffold-Diversity Synthesis of Biologically Intriguing Cyclic Sulfonamides

A “branching–folding” synthetic strategy that affords a range of diverse cyclic benzo-sulfonamide scaffolds is presented. Whereas different annulation reactions on common ketimine substrates build the branching phase of the scaffold synthesis, a common hydrogenative ring-expansion method, facilitated by an increase of the ring-strain during the branching phase, led to sulfonamides bearing medium-sized rings in a folding pathway. Cell painting assay was successfully employed to identify tubulin targeting sulfonamides as novel mitotic inhibitors.

Catalytic [2+2] and [3+2] cycloaddition reactions of allenoates with cyclic ketimines

Cyclic ketimines as electrophiles for [2+2] and [3+2] cycloaddition reactions of allenoates have been developed, affording functionalized sultam-fused azetidines and dihydropyrroles, respectively, in good yields with high regioselectivities. The Royal Soc